Lobelia inflata (Indian tobacco, puke weed) is a species of Lobelia native to eastern North America, from southeastern Canada (Nova Scotia to southeast Ontario) south through the eastern United States to Alabama and west to Kansas.
Lobelia inflata is an annual or biennial herbaceous plant. It has violet flowers that are tinted yellow on the inside, and usually appear in mid-summer and continue to bloom into Autumn
It is used medicinally in the present day; however, there are adverse effects that limit its use. Side effects can include sweating, nausea, vomiting, diarrhoea, tremors, rapid heartbeat, mental confusion, convulsions, hypothermia, coma, and possibly death.